Consumer preference and brand team desires for differentiation are driving manufacturers to remove preservatives from formulations, because they can create adverse reactions in many patients. The side effects of preservatives include irritation of the nasal passages, nose bleeds, allergic reactions and tissue thinning or damage – particularly a concern with chronic medication usage. A research showed that 80% of patients prefer preservative-free medications, and they are often willing to pay more for them. The research also found that the vast majority of physicians and pharmacists prefer prescribing or recommending preservative-free medications.
The major benefit to pharmaceutical companies using Preservative-free nasal pump of BONA is that they are able to reduce or remove the preservatives in their product, meeting the requirements of market and patients, meaning sensitive formulations can become viable marketed products as well.